How E Cigarettes Affect Your Body Smoking or vaping both harm your health., They damage your lungs, strain your heart, weaken immunity, and reduce overall well being., Choosing less harmful doesnt mean choosing safe., Your health What Does Vaping Do to Your Lungs? Johns Hopkins Medicine E cigarettes: Facts, stats and regulations Vaping releases toxic chemicals, including heavy metals, as well as ultrafine particles that go deep into the lungs. These increase the risk of heart and lung disorders.