Oral Malignant Melanoma Oral Cancer Foundation Information and Resources about Oral Head and Neck Cancer Oral melanoma and other pigmentations: when to biopsy? Lambertini 2018 Journal of the European Academy of Dermatology and Venereology Wiley Online Library Oral malignant melanoma: a rarity! BMJ Case Reports Pigmented Lesions Springer Nature Link Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule.