Tylenol, Autism, And The Glutathione Connection OC Integrative Medicine Since Tylenol is such a hot topic right now, did you know it depletes glutathione levels? When your body processes Tylenol in the liver, one of the pathways creates a toxic byproduct. To neutralize Acetaminophen metabolism Acetaminophen (4 Acetamidophenol, APAP, 4' Hydroxyacetanilide, NSC 3991, NSC 109028, Paracetamol, CAS Number: 103 90 2) Cayman Chemical Could Tylenol be making your child's health worse? Acetaminophen is widely used for pain and fever relief, but research suggests it depletes glutathione, a powerful antioxidant essential for immune function,