Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Brain peptides in Alzheimer's disease pathophysiology and therapeutic advances Cell and Tissue Research Springer Nature Link PDF) AngIV Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP PS1 Mouse via the PI3K AKT Signaling Pathway Frontiers Hepatocyte growth factor mimetic protects lateral line hair cells from aminoglycoside exposure Characterisation of the non oxidative degradation pathway of dehydroascorbic acid in slightly acidic aqueous solution ScienceDirect