G6PD Deficiency Glucose 6 phosphate dehydrogenase deficiency X linked recessive disorder Leads to low NADPH, impairing glutathione regeneration RBCs are vulnerable to oxidative damage Pathophysiology: In G6PD deficiency: No The Multiple Roles of Glucose 6 Phosphate Dehydrogenase in Tumorigenesis and Cancer Chemoresistance Clinical associations and potential cellular mechanisms linking G6PD deficiency and atherosclerotic cardiovascular disease npj Metabolic Health and Disease Glucose 6 Phosphate Dehydrogenase Deficiency Hematology & Oncology UWorld Medical Library Glucose 6 Phosphate: Metabolism and Functions