Glutathione Face Serum 1 Gallon Bloommiracle Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic Glutathione deficiency can lead to a variety of signs and symptoms that affect your overall health. Here are some common signs to look out for: 1. **Increased Dark Spots** Glutathione Glutathione depletion mediated in situ transformation of Prussian blue nanocubes for enhanced tumor specific imaging and photoimmunotherapy Inorganic Chemistry Frontiers (RSC Publishing) Glutathione depletion induces oxidative injury and apoptosis via TRPM2 channel activation in renal collecting duct cells ScienceDirect