7 Warning Signs of Pigmented Lesions: A Dentist's Guide to Causes & Care An oral melanotic macule is a harmless dark spot found on the lip, most often the lower lip, or inside the mouth, either on the gums, inside the cheek, or on the roof of the mouth. An oral melanotic Oral melanotic macule Stock Image C067 2477 Science Photo Library This lovely patient was thrilled with her beautiful result after laser treatment of oral melanotic macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding Symptoms of mouth cancer NHS