Unveiling the Role of Glutathione S transferase Protein in Breast Cancer Drug Resistance: Insights into the Signaling Pathways and Therapeutic Implications ACS Pharmacology & Translational Science In a new study published in the top scientific journal Nature, Wilmot researchers discovered that the antioxidant glutathione fuels cancer cells. This matters because it means blocking glutathione could be a new Glutamate Dehydrogenase 1 Signals through Antioxidant Glutathione Peroxidase 1 to Regulate Redox Homeostasis and Tumor Growth: Cancer Cell Multifaceted Roles of Glutathione and Glutathione Based Systems in Carcinogenesis and Anticancer Drug Resistance Elie Hatem, Nadine El Banna, Meng Er Huang, 2017 Glutathione and Xanthine Metabolic Changes in Tamoxifen Resistant Breast Cancer Cell Lines are Mediated by Down Regulation of GSS and XDH and Correlated to Poor Prognosis