Clinically important side effects of Melanotan II and placebo Download Table Melanotan is trending again. As a dermatologist, I strongly need to tell you It's an unapproved injectable peptide, and we're seeing: nausea and flushing darkening of existing moles Melanotan II: Tanning injections, nasal sprays harmful to health Melanotan is not a tan. It's an unregulated peptide with real risk. As a dermatologist, here's the reality: It has been linked to new and changing moles including cases of Melanotan II (Tan Jabs): Why They're Not Worth The Risk