Pharmacological targeting of glucose 6 phosphate dehydrogenase in human erythrocytes by Bay 117082, parthenolide and dimethyl fumarate Scientific Reports Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst G6PD enzyme mechanism and relationship with hydrogen peroxide Download Scientific Diagram The Multiple Roles of Glucose 6 Phosphate Dehydrogenase in Tumorigenesis and Cancer Chemoresistance HEMOLYTIC ANEMIA