The labial melanotic macule: a review of 79 cases What Caused These Multiple Hyperpigmented Macules of the Mouth? COM Jan. 2008 Diagnosis UW School of Dentistry Mucosal melanocytic macules An oral melanotic macule is a harmless dark spot found on the lip, most often the lower lip, or inside the mouth, either on the gums, inside the cheek, or on the roof of the mouth. An oral melanotic