Nucleotide biosynthesis links glutathione metabolism to ferroptosis sensitivity Life Science Alliance Anti proliferative effect of Cannabidiol in Prostate cancer cell PC3 is mediated by apoptotic cell death, NFB activation, increased oxidative stress, and lower reduced glutathione status PLOS One Induction of Apoptosis and Reduction of Endogenous Glutathione Level by the Ethyl Acetate Soluble Fraction of the Methanol Extract of the Roots of Potentilla fulgens in Cancer Cells PLOS One Glutathione is a critical soldier in our line of defense. We even have mechanisms that recycle and reuse it. But what happens when our toxic burden becomes too high? Our genetic detoxification Glutathione metabolism is essential for self renewal and chemoresistance of pancreatic cancer stem cells