Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Figure 1: CMAJ Here's how to make Tylenol work way better Dose it correctly: 1,000 mg at a time, spaced every 8 hours. Smaller doses don't control pain as well. Take it Is Tylenol Safe During Pregnancy? Understanding Risk Factors Seeking Health Glutathione IV vs. Pills in Los Angeles: Which One Works Better