Lip pigmentation dermoscopy: A pigmented labial lesion Happy Wednesday! , In this video, a patients labial melanotic macule (a benign pigmented lesion) is being treated with liquid nitrogen. Labial melanotic macules are flat and asymmetrical with a An oral melanotic macule is a harmless dark spot found on the lip, most often the lower lip, or inside the mouth, either on the gums, inside the cheek, or on the roof of the mouth. An oral melanotic Simultaneous occurrence of melanocytic nevus and melanotic macule in the vermilion of the lower lip ScienceDirect