Pigmented Lesions of the Oral Cavity Oral and Maxillofacial Surgery Clinics Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360 dermoscopy: A pigmented labial lesion Oral Melanotic Macule: Symptoms and Treatment Skinsight