What is Glutathione Glutathione Reporter Endogenous Deficiency of Glutathione as the Most Likely Cause of Serious Manifestations and Death in COVID 19 Patients Frontiers Case report: A Chinese patient with glutathione synthetase deficiency and a novel glutathione synthase mutation Glutathione synthetase deficiency MedLink Neurology Glutathione deficiency can lead to a variety of signs and symptoms that affect your overall health. Here are some common signs to look out for: 1. **Increased Dark Spots** Glutathione