Studies show children with autism have significantly lower levels of glutathione, the body's master antioxidant. Without enough glutathione, the body struggles to eliminate toxins, making it harder to cope with everyday Leucovorin and Autism Spectrum Disorder Emerging Clinical Insights Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain Translational Psychiatry The impact of glutathione metabolism in autism spectrum disorder ScienceDirect Tylenol can lower the body's key antioxidant, glutathione, though this isn't seen on routine labs. But mechanistic data clinical proof, so we still need good trials. The Tylenolautism link isn't clear.