Thioredoxin Glutathione Reductase from Schistosoma mansoni: An Essential Parasite Enzyme and a Key Drug Target PLOS Medicine Three dimensional structure of a mammalian thioredoxin reductase: Implications for mechanism and evolution of a selenocysteine dependent enzyme PNAS JCI Coenzyme A protects against ferroptosis via CoAlation of mitochondrial thioredoxin reductase Exploring the Thioredoxin System as a Therapeutic Target in Cancer: Mechanisms and Implications Frontiers Assigning function to active site residues of Schistosoma mansoni thioredoxin glutathione reductase from analysis of transient state reductive half reactions with variant forms of the enzyme