Improving your master antioxidant glutathione status to tame Hashimoto's low thyroid RedRiver Health and Wellness Center Glutathione Metabolism an overview ScienceDirect Topics What are good glutathione supplements for hashimoto's? Hashimoto's and Pregnancy: Impact and How to Manage It LM Your liver plays a critical role in hormone metabolism, immune balance, and detoxification. In Hashimoto's, the liver can become sluggish due to chronic inflammation, poor gut health, and an increased toxin burden.