Vaping vs. Smoking: What's the Nicotine Equivalent? Curious about how vaping compares to smoking? Let's break it down! Disposable Vapes: A typical disposable vape with around 600 puffs can JUUL 2 Pods 2 Pack Prefilled Pods Smooth Nicotine Vape DYKOne Juul pod contains as much nicotine as a pack of cigarettes. Side effects include increased heart rate and blood pressure, lung disease, chronic bronchitis and insulin resistance leading to type 2 How much nicotine is in JUUL? The Food and Drug Administration has authorized Juul Labs to keep its e cigarettes on the market, a major reversal after the agency completely banned the company's products in 2022.