Puffing Your Problems Away? CCAPSA Study finds 'strong link' between vaping and depression Vaping and the Brain: Effects of Electronic Cigarettes and E Liquid Substances The Journal of Neuropsychiatry and Clinical Neurosciences Teens who vape or smoke more likely to experience depression and anxiety, study of over 60,000 u.s. students finds. Youth using both e cigarettes and traditional tobacco report the highest levels of mental Nicotine use and stress